多孔股骨假体结构设计与性能研究

 周鑫1,粟智远2,刘林林1,石张傲1

(1.四川大学 机械工程学院,四川 成都 610065;2.西南医科大学附属医院 骨与关节外科,四川 泸州 646000)
摘要:目前的全髋关节假体股骨柄与宿主骨之间的弹性模量存在巨大的差异,这将诱导无菌性松动等长期并发症的发生。仿生多孔股骨柄能有效缓解应力遮挡带来的骨吸收问题,并通过骨细胞向内生长从而提供牢固的长期稳定性。本文旨在通过有限元分析,探讨不同多孔股骨柄在缓解骨吸收、促进骨整合方面的应用前景。提出了一种基于金刚石晶格结构的直观可视化方法,以了解孔隙大小、孔隙率与骨生长需求和增材制造约束之间的关系,并得到了金刚石晶格结构孔隙率选择的许可设计空间。随后,借助有限元的分析方法,在计算机中仿真模拟手术结果,并对多孔假体和全金属假体进行刚度以及应力遮挡率方面的评价。结果表明多孔假体在促进骨整合和缓解骨吸收方面具有明显的优势。
关键词:全髋关节置换;应力遮挡;多孔结构;孔隙率;弹性模量
中图分类号:TB124 文献标志码:A doi:10.3969/j.issn.1006-0316.2020.04.001
文章编号:1006-0316 (2020) 04-0001-05
Research on Design and Properties of Porous Femoral Prosthesis Structure
ZHOU Xin1,SU Zhiyuan2,LIU Linlin1,SHI Zhang’ao1
( 1.School of Mechanical Engineering, Sichuan University, Chengdu 610065, China; 2.Department of Orthopaedics and Joint Surgery, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China )
Abstract:There is a large gap between the elastic modulus of the fully dense femoral stem of total hip prosthesis and the host bone. This may cause long-term complications, for example, aseptic loosening, which eventually lead to revision surgery. The biomimetic porous femoral stem can effectively alleviate bone resorption caused by stress shielding and provide firm and long-term implant fixation through the inward growth of bone cells. The purpose of this research is to investigate the application prospect of different porous femoral stem in relieving bone resorption and promoting osseointegration by finite element analysis. We have presented a visualization method based on diamond lattice structure to understand the relationship between pore size, porosity, and bone growth and additive manufacturing constraints, and to make porosity selection in the design of diamond lattice structure. The results of the models’ mechanical performance is obtained with finite element analysis method. Stiffness and stress shielding rates for porous prostheses and all-metal prostheses are evaluated. The results indicate that the porous prosthesis has significant advantages in promoting osseointegration and alleviating bone resorption.
Key words:total hip arthroplasty;stress shielding;porous structure;porosity;elastic modulus
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收稿日期:2019-10-24
基金项目:国家重点研发计划(2016YFC1100600);国家自然科学基金(61540006)
作者简介:周鑫(1994-),男,江西九江人,硕士研究生,主要研究方向为人工假体的力学分析和设计,zhouxin_1994@foxmail.com;粟智远(1994-),男,四川宜宾人,硕士研究生,主要研究方向为人工关节置换术;刘林林(1989-),男,山西运城人,博士研究生,主要研究方向为骨组织植入物的设计;石张傲(1992-),男,安徽安庆人,硕士研究生,主要研究方向为骨组织植入物的设计。
 

 

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