基于TPMS建模方法进行仿生骨支架结构设计
石张傲,周鑫
(四川大学 机械工程学院,四川 成都 610065)
摘要:为了更好地拟合出人体骨细胞生存生长的多孔曲面环境,采用基于函数的极小三周期曲面(TPMS)建模方法,来进行仿生骨支架结构的设计。采用这种方法,能够通过调整函数的相关参数,实现对仿生骨支架孔径大小以及孔隙率大小的精准控制。选取了TPMS结构中的一种P曲面结构,通过与人体真实骨组织结构单元孔径大小以及孔隙率大小进行比对,选定了P曲面结构的参数值u,并确定了仿生骨支架合理的单元尺寸,最后通过有限元仿真软件对模型进行了力学分析及评估,结果表明,设计的支架结构具有更匹配人体骨结构的力学性能,对指导构建人工骨支架结构具有重要意义。
关键词:TPMS;人工骨支架;有限元分析
中图分类号:R687.4 文献标志码:A doi:10.3969/j.issn.1006-0316.2020.03.001
文章编号:1006-0316 (2020) 03-0001-06
The Bionic Bone Scaffold Structure Design Based on the Triply Periodic Minimal Surface Modeling Method
SHI Zhang’ao,ZHOU Xin
( School of Mechanical and Engineering, Sichuan University, Chengdu 610065, China )
Abstract:In order to better fit the porous surface environment for the survival and growth of human bone cells, in this paper, a function of the triply periodic minimal surface modeling method (TPMS) is adopted to design the bionic bone scaffold structure. With this method, the pore size and porosity of the bionic bone scaffold can be precisely controlled by adjusting the relevant parameters of the function. In this paper, one of the TPMS structures, p-curved surface structure is selected. By comparing it with the pore size and porosity of the real bone structure unit of human body, the parameter value u of p-curved surface structure is selected, and the reasonable unit size of the bionic bone scaffold is determined. Finally, the mechanical analysis and evaluation of the model are carried out by finite element simulation software. The result shows that the designed scaffold structure can better match the mechanical properties of human bone structure, which is of great significance for the construction of artificial bone scaffold structure.
Key words:TPMS;artificial bone scaffold;finite element analysis
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收稿日期:2019-10-12
基金项目:国家重点研发计划(2016YFC1100600);国家自然科学基金(61540006)
作者简介:石张傲(1992-),男,安徽安庆人,硕士研究生,主要研究方向为骨组织工程。
 

 

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